Recent Publications

Publications from the last five years are listed here. For older publications, please visit Susan Schenk’s Google Scholar profile.

Webster J, Harper D, Schenk S. (2017) Generalization of serotonin and dopamine ligands to the discriminative stimulus effects of different doses of MDMA. Behav Pharmacol, 28: 245-254.

Schenk S, Bradbury S (2015) Persistent sensitization to the locomotor activating effects of MDMA following MDMA self-administration in rats. Pharmacol Biocehm Behav, 132: 103-107.

Van de Wetering R, Schenk S. (2017) Role of dopamine D2 receptors in sensitization to the behavioral effects of MDMA: Self administration and locomotor activity studies. Psychopharamcology 234:1155-1164.

Schenk S, Foote J, Aronsen D, Bukholt N, Van de Wetering R, Webster J. (2016) Serotonin antagonists fail to alter MDMA self-administration in rats. Pharmacol Biochem Behav 148: 38-45.

Aronsen D, Schenk S (2016) MDMA self-administration fails to alter the behavioral response to 5-HT1A and 5-HT1B agonists. Psychopharmacology, 233:1323-1330.

Webster J, Harper D, Schenk S. (2016) Analysis of the Acquisition of Drug Discrimination Reveals Differences Between a High vs Low Training Dose of ±3,4-methylenedioxymethamphetamine (MDMA). Journal of Drug and Alcohol Research, 5: art235976. doi:10.4303/jdar/235976

Aronsen D, Bukholt N, Schenk S. (2016) Repeated administration of the 5-HT1B/1A agonist, RU 24969, facilitates the acquisition of MDMA self-administration: Role of 5-HT1A and 5-HT1B receptor mechanisms. Psychopharmacology, 233:1339-1347.

Lee L, Goodman L, Fourie C, Schenk S, Leitch B, Montgomery JM (2016) AMPA receptors as therapeutic targets for neurological disorders. Advances in Protein Chemistry and Structural Biology, 103:203-261.

Aronsen, D., Webster, J., & Schenk, S. (2014). RU 24969-produced adipsia and hyperlocomotion: Differential role of 5HT1A and 5HT1B receptor mechanisms. Pharmacology, Biochemistry and Behavior, 124, 1-4.

Bradbury, S., Bird, J., Colussi-Mas, J., Mueller, M., Ricaurte, G., & Schenk, S. (2014). Acquisition of MDMA self-administration: Pharmacokinetic factors and MDMA-induced serotonin release. Addiction Biology, 19(5), 874-884. doi:10.1111/adb.12069

Harper, D. N., Langen, A., & Schenk, S. (2014). A 3-lever discrimination procedure reveals differences in the subjective effects of low and high doses of MDMA. Pharmacology, Biochemistry, and Behavior, 116, 9-15. doi:10.1016/j.pbb.2013.11.011

Oakly, A. C., Brox, B. W., Schenk, S., & Ellenbroek, B. A. (2014). A genetic deletion of the serotonin transporter greatly enhances the reinforcing properties of MDMA in rats. Molecular Psychiatry, 19(5), 534-535. doi:10.1038/mp.2013.75

Bird, J., & Schenk, S. (2013). Contribution of impulsivity and novelty-seeking to the acquisition and maintenance of MDMA self-administration. Addiction Biology, 18(4), 654-664. doi:10.1111/j.1369-1600.2012.00477.x

Schenk, S., Abraham, B., Aronsen, D., Colussi-Mas, J., & Do, J. (2013). Effects of repeated exposure to MDMA on 5HT(1a) autoreceptor function: Behavioral and neurochemical responses to 8-OHDPAT. Psychopharmacology, 227(2), 355.

Do, J., & Schenk, S. (2013). Self-administered MDMA produces dose- and time-dependent serotonin deficits in the rat brain. Addiction Biology, 18(3), 441-447. doi:10.1111/j.1369-1600.2011.00370.x

Bradbury, S., Gittings, D., & Schenk, S. (2012). Repeated exposure to MDMA and amphetamine: Sensitization, cross-sensitization, and response to dopamine D1- and D2-like agonists. Psychopharmacology, 223(4), 389-399. doi:10.1007/s00213-012-2726-9

Morani, A. S., Schenk, S., Prisinzano, T. E., & Kivell, B. M. (2012). A single injection of a novel κ opioid receptor agonist salvinorin A attenuates the expression of cocaine-induced behavioral sensitization in rats. Behavioural Pharmacology, 23(2), 162.

Schenk, S., Colussi-Mas, J., Do, J., & Bird, J. (2012). Profile of MDMA self-administration from a large cohort of rats: MDMA develops a profile of dependence with extended testing. Journal of Drug and Alcohol Research, 1, 1-6. doi:10.4303/jdar/235602

Ali, S. F., Onaivi, E. S., Dodd, P. R., Cadet, J. L., Schenk, S., Kuhar, M. J., & Koob, G. F. (2011). Understanding the global problem of drug addiction is a challenge for IDARS scientists. Current Neuropharmacology, 9(1), 2-7. doi:10.2174/157015911795017245

Schenk, S., Gittings, D., & Colussi-Mas, J. (2011). Dopaminergic mechanisms of reinstatement of MDMA-seeking behaviour in rats. British Journal of Pharmacology, 162(8), 1770-1780. doi:10.1111/j.1476-5381.2010.01193.x

Schenk, S. (2011). MDMA (“ecstasy”) abuse as an example of dopamine neuroplasticity. Neuroscience and Biobehavioral Reviews, 35(5), 1203-1218. doi:10.1016/j.neubiorev.2010.12.010

Schenk, S., Harper, D. N., & Do, J. (2011). Novel object recognition memory: Measurement issues and effects of MDMA self-administration following short inter-trial intervals. Journal of Psychopharmacology, 25(8), 1043-1052. doi:10.1177/0269881110389213

Carati, C., & Schenk, S. (2011). Role of dopamine D1- and D2-like receptor mechanisms in drug-seeking following methamphetamine self-administration in rats. Pharmacology, Biochemistry and Behavior, 98(3), 449-454. doi:10.1016/j.pbb.2011.02.010

Brennan, K. A., Colussi-Mas, J., Carati, C., Lea, R. A., Fitzmaurice, P. S., & Schenk, S. (2010). Methamphetamine self-administration and the effect of contingency on monoamine and metabolite tissue levels in the rat. Brain Research, 1317, 137-146. doi:10.1016/j.brainres.2009.11.069

Colussi-Mas, J., Wise, R. J., Howard, A., & Schenk, S. (2010). Drug seeking in response to a priming injection of MDMA in rats: Relationship to initial sensitivity to self-administered MDMA and dorsal striatal dopamine. The International Journal of Neuropsychopharmacology, 13(10), 1315-1327. doi:10.1017/S1461145710000283

Jones, K., Brennan, K. A., Colussi-Mas, J., & Schenk, S. (2010). Tolerance to 3,4-methylenedioxymethamphetamine is associated with impaired serotonin release. Addiction Biology, 15(3), 289-298. doi:10.1111/j.1369-1600.2010.00217.x

Brennan, K. A., Carati, C., Lea, R. A., Fitzmaurice, P. S., & Schenk, S. (2010). Role of D1- and D2-like receptors in 3,4-methylenedioxymethamphetamine and methamphetamine self-administration in rats. Behavioural Pharmacology, 20, 688-194.

Kivell, B., Day, D., Bosch, P., Schenk, S., & Miller, J. (2010). MDMA causes a p38-mitogen-activated protein kinase-independent redistribution of serotonin transporter from the cell-surface to intracellular vesicles. Neuroscience, 168, 82-95.