Recent Publications

Selected publications from the last five years are listed here. For older publications, please visit Susan Schenk’s Google Scholar profile.

Schenk S, Highgate Q (2018) Dopamine and Serotonin Antagonists Fail to Alter the Discriminative Stimulus Properties of +/- methylenedioxymethamphetamine (MDMA). Behav Pharmacol, 30:327-334.

Highgate Q, Schenk S (2018) Comparison of the Effects of Abstinence on MDMA and Cocaine Self-Administration in Rats. Psychopharmacology, 235:3233-3241.

Schenk S, Newcombe D (2018) Methylenedioxymethamphetamine (MDMA) in Psychiatry: Pros, cons and suggestions. J Clin Psychopharmacol, 38:632-638

Webster J, Harper D, Schenk S. (2017) Generalization of serotonin and dopamine ligands to the discriminative stimulus effects of different doses of MDMA. Behav Pharmacol, 28: 245-254.

Schenk S, Bradbury S (2015) Persistent sensitization to the locomotor activating effects of MDMA following MDMA self-administration in rats. Pharmacol Biocehm Behav, 132: 103-107.

Van de Wetering R, Schenk S. (2017) Role of dopamine D2 receptors in sensitization to the behavioral effects of MDMA: Self administration and locomotor activity studies. Psychopharamcology 234:1155-1164.

Schenk S, Foote J, Aronsen D, Bukholt N, Van de Wetering R, Webster J. (2016) Serotonin antagonists fail to alter MDMA self-administration in rats. Pharmacol Biochem Behav 148: 38-45.

Aronsen D, Schenk S (2016) MDMA self-administration fails to alter the behavioral response to 5-HT1A and 5-HT1B agonists. Psychopharmacology, 233:1323-1330.

Webster J, Harper D, Schenk S. (2016) Analysis of the Acquisition of Drug Discrimination Reveals Differences Between a High vs Low Training Dose of ±3,4-methylenedioxymethamphetamine (MDMA). Journal of Drug and Alcohol Research, 5: art235976. doi:10.4303/jdar/235976

Aronsen D, Bukholt N, Schenk S. (2016) Repeated administration of the 5-HT1B/1A agonist, RU 24969, facilitates the acquisition of MDMA self-administration: Role of 5-HT1A and 5-HT1B receptor mechanisms. Psychopharmacology, 233:1339-1347.

Lee L, Goodman L, Fourie C, Schenk S, Leitch B, Montgomery JM (2016) AMPA receptors as therapeutic targets for neurological disorders. Advances in Protein Chemistry and Structural Biology, 103:203-261.

Aronsen, D., Webster, J., & Schenk, S. (2014). RU 24969-produced adipsia and hyperlocomotion: Differential role of 5HT1A and 5HT1B receptor mechanisms. Pharmacology, Biochemistry and Behavior, 124, 1-4.

Bradbury, S., Bird, J., Colussi-Mas, J., Mueller, M., Ricaurte, G., & Schenk, S. (2014). Acquisition of MDMA self-administration: Pharmacokinetic factors and MDMA-induced serotonin release. Addiction Biology, 19(5), 874-884. doi:10.1111/adb.12069

Harper, D. N., Langen, A., & Schenk, S. (2014). A 3-lever discrimination procedure reveals differences in the subjective effects of low and high doses of MDMA. Pharmacology, Biochemistry, and Behavior, 116, 9-15. doi:10.1016/j.pbb.2013.11.011

Oakly, A. C., Brox, B. W., Schenk, S., & Ellenbroek, B. A. (2014). A genetic deletion of the serotonin transporter greatly enhances the reinforcing properties of MDMA in rats. Molecular Psychiatry, 19(5), 534-535. doi:10.1038/mp.2013.75

Bird, J., & Schenk, S. (2013). Contribution of impulsivity and novelty-seeking to the acquisition and maintenance of MDMA self-administration. Addiction Biology, 18(4), 654-664. doi:10.1111/j.1369-1600.2012.00477.x

Schenk, S., Abraham, B., Aronsen, D., Colussi-Mas, J., & Do, J. (2013). Effects of repeated exposure to MDMA on 5HT(1a) autoreceptor function: Behavioral and neurochemical responses to 8-OHDPAT. Psychopharmacology, 227(2), 355.

Do, J., & Schenk, S. (2013). Self-administered MDMA produces dose- and time-dependent serotonin deficits in the rat brain. Addiction Biology, 18(3), 441-447. doi:10.1111/j.1369-1600.2011.00370.x

Bradbury, S., Gittings, D., & Schenk, S. (2012). Repeated exposure to MDMA and amphetamine: Sensitization, cross-sensitization, and response to dopamine D1- and D2-like agonists. Psychopharmacology, 223(4), 389-399. doi:10.1007/s00213-012-2726-9

Morani, A. S., Schenk, S., Prisinzano, T. E., & Kivell, B. M. (2012). A single injection of a novel κ opioid receptor agonist salvinorin A attenuates the expression of cocaine-induced behavioral sensitization in rats. Behavioural Pharmacology, 23(2), 162.

Schenk, S., Colussi-Mas, J., Do, J., & Bird, J. (2012). Profile of MDMA self-administration from a large cohort of rats: MDMA develops a profile of dependence with extended testing. Journal of Drug and Alcohol Research, 1, 1-6. doi:10.4303/jdar/235602

Ali, S. F., Onaivi, E. S., Dodd, P. R., Cadet, J. L., Schenk, S., Kuhar, M. J., & Koob, G. F. (2011). Understanding the global problem of drug addiction is a challenge for IDARS scientists. Current Neuropharmacology, 9(1), 2-7. doi:10.2174/157015911795017245

Schenk, S., Gittings, D., & Colussi-Mas, J. (2011). Dopaminergic mechanisms of reinstatement of MDMA-seeking behaviour in rats. British Journal of Pharmacology, 162(8), 1770-1780. doi:10.1111/j.1476-5381.2010.01193.x

Schenk, S. (2011). MDMA (“ecstasy”) abuse as an example of dopamine neuroplasticity. Neuroscience and Biobehavioral Reviews, 35(5), 1203-1218. doi:10.1016/j.neubiorev.2010.12.010

Schenk, S., Harper, D. N., & Do, J. (2011). Novel object recognition memory: Measurement issues and effects of MDMA self-administration following short inter-trial intervals. Journal of Psychopharmacology, 25(8), 1043-1052. doi:10.1177/0269881110389213

Carati, C., & Schenk, S. (2011). Role of dopamine D1- and D2-like receptor mechanisms in drug-seeking following methamphetamine self-administration in rats. Pharmacology, Biochemistry and Behavior, 98(3), 449-454. doi:10.1016/j.pbb.2011.02.010

Brennan, K. A., Colussi-Mas, J., Carati, C., Lea, R. A., Fitzmaurice, P. S., & Schenk, S. (2010). Methamphetamine self-administration and the effect of contingency on monoamine and metabolite tissue levels in the rat. Brain Research, 1317, 137-146. doi:10.1016/j.brainres.2009.11.069

Colussi-Mas, J., Wise, R. J., Howard, A., & Schenk, S. (2010). Drug seeking in response to a priming injection of MDMA in rats: Relationship to initial sensitivity to self-administered MDMA and dorsal striatal dopamine. The International Journal of Neuropsychopharmacology, 13(10), 1315-1327. doi:10.1017/S1461145710000283

Jones, K., Brennan, K. A., Colussi-Mas, J., & Schenk, S. (2010). Tolerance to 3,4-methylenedioxymethamphetamine is associated with impaired serotonin release. Addiction Biology, 15(3), 289-298. doi:10.1111/j.1369-1600.2010.00217.x

Brennan, K. A., Carati, C., Lea, R. A., Fitzmaurice, P. S., & Schenk, S. (2010). Role of D1- and D2-like receptors in 3,4-methylenedioxymethamphetamine and methamphetamine self-administration in rats. Behavioural Pharmacology, 20, 688-194.

Kivell, B., Day, D., Bosch, P., Schenk, S., & Miller, J. (2010). MDMA causes a p38-mitogen-activated protein kinase-independent redistribution of serotonin transporter from the cell-surface to intracellular vesicles. Neuroscience, 168, 82-95.